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GUIDE

Peptides for Growth Hormone Pathways

Compares GHRH analogs, ghrelin agonists, and non-peptide secretagogues.

What to ask your clinician

Which claims are label-based, which are investigational, and which safety warnings apply to your situation?

Evidence distinction

Human randomized data, observational reports, animal studies, and marketing claims are ranked separately.

Regulatory distinction

Approved medications, supplements, cosmetic ingredients, compounded products, and RUO compounds are not equivalent.

Plain-English guide

Compares GHRH analogs, ghrelin agonists, and non-peptide secretagogues.

Use this guide as a map, not a recommendation list. Start by separating approved product labels from research-only, supplement, cosmetic, and marketing claims. Then compare evidence grade, route, safety score, and source quality before reading individual peptide profiles.

For any peptide with an approved product context, the official label is the primary source for indications, warnings, contraindications, and adverse reactions. For investigational or research-use-only entries, treat the profile as a source-review starting point rather than proof of safety or effectiveness.

Ranked entries

Abaloparatide

Osteoporosis medication context depending on product label

AApproved

ACTH

Adrenal-axis physiology and medication context

CUnknown

Adropin

Energy homeostasis and vascular research

CUnknown

Alpha-MSH

Pigmentation, inflammation, and melanocortin pathway research

CInvestigational

Amylin

Satiety and glucose-regulation research

CUnknown

Angiotensin II

Vasodilatory shock medication context depending on product label

AApproved

AOD-9604

Metabolic and body-composition research

CInvestigational

Bivalirudin

Anticoagulant medication context depending on product label

AApproved

BPC-157

Tissue repair and gut pathway research

DResearch Use Only

Bremelanotide

FDA-approved product context for acquired, generalized hypoactive sexual desire disorder in premenopausal women

AApproved

Calcitonin salmon

Bone and calcium metabolism medication context depending on product label

AApproved

Cetrorelix

Assisted reproduction medication context depending on product label

AApproved

CJC-1295

Growth hormone pathway research

CInvestigational

Corticorelin

Diagnostic medication context depending on product label availability

AApproved

Cosyntropin

Adrenal-axis diagnostic medication context depending on product label

AApproved

CRH

Stress-axis and endocrine research

CUnknown

C-type natriuretic peptide

Bone growth and cardiovascular research

CUnknown

Dasiglucagon

Severe hypoglycemia medication context depending on product label

AApproved

Degarelix

Hormone-axis medication context depending on product label

AApproved

Desmopressin

Antidiuretic hormone analog indications depending on product label

AApproved

Dulaglutide

Type 2 diabetes medication context depending on product label

AApproved

Enfuvirtide

Antiretroviral medication context depending on product label

AApproved

Epitalon

Aging and telomere pathway research

EInvestigational

Eptifibatide

Cardiology medication context depending on product label

AApproved

Exenatide

Type 2 diabetes medication context depending on product label

AApproved

Ganirelix

Assisted reproduction medication context depending on product label

AApproved

Ghrelin

Appetite, metabolism, and growth hormone pathway research

CInvestigational

GIP

Metabolic signaling and incretin medicine context

CUnknown

GLP-1

Metabolic signaling and incretin medicine context

CUnknown

GLP-2

Intestinal adaptation and gut physiology research

CUnknown

Glucagon

Severe hypoglycemia rescue and diagnostic contexts depending on product label

AApproved

Goserelin

Hormone-axis medication context depending on product label

AApproved

HCG

Hormone medication context; included because users search it near peptides

AApproved

Ibutamoren / MK-677

Growth hormone secretagogue comparison item

CNot Approved

Icatibant

Hereditary angioedema medication context depending on product label

AApproved

Insulin

Diabetes medication context depending on insulin product

AApproved

Ipamorelin

Growth hormone secretagogue research

DInvestigational

Lanreotide

Endocrine and neuroendocrine medication context depending on product label

AApproved

Leuprolide

Hormone-axis medication context depending on product label

AApproved

Linaclotide

Gastrointestinal medication context depending on product label

AApproved

Liraglutide

Weight management and type 2 diabetes depending on product label

AApproved

Lixisenatide

Type 2 diabetes medication context depending on product label

AApproved

Mecasermin

Growth failure medication context depending on product label

AApproved

Nafarelin

Hormone-axis medication context depending on product label

AApproved

Nesiritide

Cardiovascular medication context depending on product label and market status

AApproved

Octreotide

Endocrine and neuroendocrine tumor symptom medication context depending on product label

AApproved

Oxyntomodulin

Metabolic and appetite-regulation research

CInvestigational

Oxytocin

Obstetric medication context and neuroendocrine research

AApproved

Pasireotide

Endocrine medication context depending on product label

AApproved

Pegvisomant

Acromegaly medication context depending on product label

AApproved

Plecanatide

Gastrointestinal medication context depending on product label

AApproved

Pramlintide

Diabetes medication context as an amylin analog

AApproved

Protirelin

Historical diagnostic medication context depending on product label availability

AApproved

Secretin human

Diagnostic medication context depending on product label

AApproved

Selank

Anxiety, cognition, and neuropeptide research

CInvestigational

Semaglutide

Weight management and type 2 diabetes, depending on product label

AApproved

Semax

Cognition and neurological research

CInvestigational

Sermorelin

Growth hormone pathway research and historical diagnostic/therapeutic contexts

CInvestigational

Setmelanotide

Rare genetic obesity medication context depending on product label

AApproved

Somatostatin

Endocrine and gastrointestinal signaling research

CUnknown

Somatropin

Growth hormone replacement medication context depending on product label

AApproved

Teduglutide

Short bowel syndrome medication context depending on product label

AApproved

Teriparatide

Osteoporosis medication context depending on product label

AApproved

Tesamorelin

Reduction of excess abdominal fat in HIV-associated lipodystrophy

AApproved

Thymulin

Immune and endocrine research

DResearch Use Only

Tirzepatide

Weight management, obstructive sleep apnea in adults with obesity, and type 2 diabetes depending on product label

AApproved

TRH

Hypothalamic-pituitary-thyroid axis research

CUnknown

Triptorelin

Hormone-axis medication context depending on product label

AApproved

Vasopressin

Shock, diabetes insipidus, and procedural medication contexts depending on product label

AApproved

VIP

Pulmonary, vascular, and neuroimmune pathway research

CInvestigational

Vosoritide

Achondroplasia medication context depending on product label

AApproved

Ziconotide

Severe chronic pain medication context depending on product label

AApproved