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GUIDE

FDA-Approved Peptide Medications

Database view for approved prescription peptide or peptide-adjacent medicines.

What to ask your clinician

Which claims are label-based, which are investigational, and which safety warnings apply to your situation?

Evidence distinction

Human randomized data, observational reports, animal studies, and marketing claims are ranked separately.

Regulatory distinction

Approved medications, supplements, cosmetic ingredients, compounded products, and RUO compounds are not equivalent.

Plain-English guide

Database view for approved prescription peptide or peptide-adjacent medicines.

Use this guide as a map, not a recommendation list. Start by separating approved product labels from research-only, supplement, cosmetic, and marketing claims. Then compare evidence grade, route, safety score, and source quality before reading individual peptide profiles.

For any peptide with an approved product context, the official label is the primary source for indications, warnings, contraindications, and adverse reactions. For investigational or research-use-only entries, treat the profile as a source-review starting point rather than proof of safety or effectiveness.

Ranked entries

Abaloparatide

Osteoporosis medication context depending on product label

AApproved

Acetyl tetrapeptide-3

Topical hair and skin-care ingredient context

CCosmetic

ACTH

Adrenal-axis physiology and medication context

CUnknown

Adrenomedullin

Cardiovascular and vascular biology research

CInvestigational

Adropin

Energy homeostasis and vascular research

CUnknown

Alpha-MSH

Pigmentation, inflammation, and melanocortin pathway research

CInvestigational

Amylin

Satiety and glucose-regulation research

CUnknown

Angiotensin II

Vasodilatory shock medication context depending on product label

AApproved

Anidulafungin

Invasive fungal infection medication context depending on product label

AApproved

AOD-9604

Metabolic and body-composition research

CInvestigational

Apelin

Cardiovascular and metabolic pathway research

CInvestigational

Argireline

Topical cosmetic expression-line ingredient context

CCosmetic

Atrial natriuretic peptide

Cardiovascular and fluid-balance research

CUnknown

Aviptadil

Pulmonary and critical-care research

CInvestigational

Bacitracin

Topical or ophthalmic antibacterial medication context depending on product label

AApproved

Beta-endorphin

Pain, stress, and neuroendocrine research

CInvestigational

Biotinoyl tripeptide-1

Topical hair-care ingredient context

CCosmetic

Bivalirudin

Anticoagulant medication context depending on product label

AApproved

BPC-157

Tissue repair and gut pathway research

DResearch Use Only

Bradykinin

Inflammation, vascular permeability, and angioedema pathway research

CInvestigational

Bremelanotide

FDA-approved product context for acquired, generalized hypoactive sexual desire disorder in premenopausal women

AApproved

Cagrilintide

Weight management and metabolic research

CInvestigational

Calcitonin gene-related peptide

Migraine, vascular, and sensory signaling research

CUnknown

Calcitonin salmon

Bone and calcium metabolism medication context depending on product label

AApproved

Caspofungin

Invasive fungal infection medication context depending on product label

AApproved

Cetrorelix

Assisted reproduction medication context depending on product label

AApproved

Cilengitide

Oncology research

CInvestigational

CJC-1295

Growth hormone pathway research

CInvestigational

Colistin

Resistant Gram-negative infection medication context depending on product label

AApproved

Collagen peptides

Skin, joint, and nutrition supplement context

CSupplement

Corticorelin

Diagnostic medication context depending on product label availability

AApproved

Cosyntropin

Adrenal-axis diagnostic medication context depending on product label

AApproved

Creatine

Sports nutrition comparison item

BNot Approved

CRH

Stress-axis and endocrine research

CUnknown

C-type natriuretic peptide

Bone growth and cardiovascular research

CUnknown

Cyclosporine

Transplant, ophthalmic, or immune-mediated medication context depending on product label

AApproved

Dalbavancin

Skin and soft tissue infection medication context depending on product label

AApproved

Daptomycin

Gram-positive infection medication context depending on product label

AApproved

Dasiglucagon

Severe hypoglycemia medication context depending on product label

AApproved

Degarelix

Hormone-axis medication context depending on product label

AApproved

Dermaseptin

Host-defense peptide research

DResearch Use Only

Desmopressin

Antidiuretic hormone analog indications depending on product label

AApproved

DSIP

Sleep and neuroendocrine research

EInvestigational

Dulaglutide

Type 2 diabetes medication context depending on product label

AApproved

Dynorphin

Pain, reward, and stress-pathway research

CUnknown

Elamipretide

Mitochondrial disease and Barth syndrome research or regulated context depending on jurisdiction/date

CInvestigational

Emerging peptide placeholder

Placeholder for future source-backed peptide entries

EUnknown

Enfuvirtide

Antiretroviral medication context depending on product label

AApproved

Enkephalin

Pain and reward-pathway research

CUnknown

Enlicitide decanoate

Hypercholesterolemia research

CInvestigational

Epitalon

Aging and telomere pathway research

EInvestigational

Eptifibatide

Cardiology medication context depending on product label

AApproved

Exenatide

Type 2 diabetes medication context depending on product label

AApproved

Galanin

Appetite, pain, mood, and neuroendocrine research

CUnknown

Ganirelix

Assisted reproduction medication context depending on product label

AApproved

GHK-Cu

Cosmetic skin-care ingredient and wound/skin biology research

CCosmetic

Ghrelin

Appetite, metabolism, and growth hormone pathway research

CInvestigational

GIP

Metabolic signaling and incretin medicine context

CUnknown

GLP-1

Metabolic signaling and incretin medicine context

CUnknown

GLP-2

Intestinal adaptation and gut physiology research

CUnknown

Glucagon

Severe hypoglycemia rescue and diagnostic contexts depending on product label

AApproved

Goserelin

Hormone-axis medication context depending on product label

AApproved

Gramicidin

Topical/ophthalmic antibacterial ingredient context depending on product label

AApproved

HCG

Hormone medication context; included because users search it near peptides

AApproved

Hexapeptide-11

Topical skin-care ingredient context

CCosmetic

Humanin

Aging, metabolism, and cellular stress research

CUnknown

Ibutamoren / MK-677

Growth hormone secretagogue comparison item

CNot Approved

Icatibant

Hereditary angioedema medication context depending on product label

AApproved

Insulin

Diabetes medication context depending on insulin product

AApproved

Ipamorelin

Growth hormone secretagogue research

DInvestigational

Kisspeptin

Reproductive endocrinology and GnRH-axis research

CInvestigational

KPV

Inflammatory and gut pathway research

DResearch Use Only

Lactoferricin

Antimicrobial and immune research

DResearch Use Only

Lanreotide

Endocrine and neuroendocrine medication context depending on product label

AApproved

Leuprolide

Hormone-axis medication context depending on product label

AApproved

Linaclotide

Gastrointestinal medication context depending on product label

AApproved

Liraglutide

Weight management and type 2 diabetes depending on product label

AApproved

Lixisenatide

Type 2 diabetes medication context depending on product label

AApproved

LL-37

Innate immunity and antimicrobial pathway research

DResearch Use Only

Lunasin

Nutrition and cell-signaling research

DResearch Use Only

Magainin

Host-defense peptide research

DResearch Use Only

Matrixyl

Topical cosmetic skin-care ingredient context

CCosmetic

Mazdutide

Obesity and type 2 diabetes research

CInvestigational

Mecasermin

Growth failure medication context depending on product label

AApproved

Micafungin

Invasive fungal infection medication context depending on product label

AApproved

MOTS-c

Metabolic and aging-pathway research

DInvestigational

Nafarelin

Hormone-axis medication context depending on product label

AApproved

Nesfatin-1

Appetite and metabolic research

CUnknown

Nesiritide

Cardiovascular medication context depending on product label and market status

AApproved

Neuropeptide Y

Appetite, stress, vascular, and nervous-system research

CInvestigational

Neurotensin

Nervous-system and gastrointestinal signaling research

CUnknown

Nisin

Food preservation and antimicrobial research context

DResearch Use Only

Octreotide

Endocrine and neuroendocrine tumor symptom medication context depending on product label

AApproved

Orexin-A

Sleep, arousal, appetite, and neurobiology research

CUnknown

Oritavancin

Skin and soft tissue infection medication context depending on product label

AApproved

Oxyntomodulin

Metabolic and appetite-regulation research

CInvestigational

Oxytocin

Obstetric medication context and neuroendocrine research

AApproved

Palmitoyl oligopeptide

Topical skin-care ingredient context

CCosmetic

Palmitoyl tetrapeptide-7

Topical skin-care ingredient context

CCosmetic

Palmitoyl tripeptide-1

Topical skin-care ingredient context

CCosmetic

Paltusotine

Acromegaly medication/research context depending on product status

CInvestigational

Pasireotide

Endocrine medication context depending on product label

AApproved

Pegvisomant

Acromegaly medication context depending on product label

AApproved

Pemvidutide

Metabolic dysfunction-associated steatohepatitis and obesity research

CInvestigational

Peptide YY

Appetite and gut-brain axis research

CInvestigational

Plecanatide

Gastrointestinal medication context depending on product label

AApproved

PNC-27

Preclinical oncology research

DResearch Use Only

Polymyxin B

Antibacterial medication context depending on product label

AApproved

Pramlintide

Diabetes medication context as an amylin analog

AApproved

Protirelin

Historical diagnostic medication context depending on product label availability

AApproved

Retatrutide

Obesity and metabolic disease research

CInvestigational

Romiplostim

Thrombocytopenia medication context depending on product label

AApproved

Saralasin

Renin-angiotensin research and historical pharmacology context

DResearch Use Only

Secretin human

Diagnostic medication context depending on product label

AApproved

Selank

Anxiety, cognition, and neuropeptide research

CInvestigational

Semaglutide

Weight management and type 2 diabetes, depending on product label

AApproved

Semax

Cognition and neurological research

CInvestigational

Sermorelin

Growth hormone pathway research and historical diagnostic/therapeutic contexts

CInvestigational

Setmelanotide

Rare genetic obesity medication context depending on product label

AApproved

SHLP-2

Metabolism and aging research

CUnknown

Somatostatin

Endocrine and gastrointestinal signaling research

CUnknown

Somatropin

Growth hormone replacement medication context depending on product label

AApproved

Substance P

Pain, inflammation, and neuroimmune research

CUnknown

Survodutide

Obesity and metabolic liver disease research

CInvestigational

Teduglutide

Short bowel syndrome medication context depending on product label

AApproved

Telavancin

Serious bacterial infection medication context depending on product label

AApproved

Teriparatide

Osteoporosis medication context depending on product label

AApproved

Tesamorelin

Reduction of excess abdominal fat in HIV-associated lipodystrophy

AApproved

Tesofensine peptide-adjacent comparison

Weight-management research comparison context

CInvestigational

Thymopoietin

Immune signaling research

DResearch Use Only

Thymosin alpha-1

Immune and infectious-disease research; approved in some non-US jurisdictions

BInvestigational

Thymulin

Immune and endocrine research

DResearch Use Only

Thymus peptides

Immune supplement and research-adjacent context

ESupplement

Tirzepatide

Weight management, obstructive sleep apnea in adults with obesity, and type 2 diabetes depending on product label

AApproved

TRH

Hypothalamic-pituitary-thyroid axis research

CUnknown

Tripeptide-29

Topical skin-care ingredient context

CCosmetic

Triptorelin

Hormone-axis medication context depending on product label

AApproved

Ularitide

Acute heart failure research

CInvestigational

Urocortin

Stress-axis and cardiovascular research

CUnknown

Vancomycin

Serious Gram-positive infection medication context depending on product label

AApproved

Vasopressin

Shock, diabetes insipidus, and procedural medication contexts depending on product label

AApproved

VIP

Pulmonary, vascular, and neuroimmune pathway research

CInvestigational

Voclosporin

Lupus nephritis medication context depending on product label

AApproved

Vosoritide

Achondroplasia medication context depending on product label

AApproved

Ziconotide

Severe chronic pain medication context depending on product label

AApproved